Unfortunately, ED is about the worst possible case for aliasing. Much of the graphics consist of parallel horizontal or vertical lines (grills, pipes, etc.). On my 4K flat monitor, I could get antialiasing to an acceptable level, but only with an unacceptable frame rate, using 2x SS in game and nVidia “dynamic super res” of 7680x4320, which yields a low single-digit frame rate (as a test, and it quickly crashed).
As for VR, I have an 8K. I use PiTool quality at 2.0 with a refresh rate of 72 and I leave smart smoothing and Fixed Fovea Rendering OFF. I use Steam VR video SS at automatic and app SS at 130%, for a per-eye rendering resolution of 3501x3084. This is a good balance of res vs color fringing (due to 8K only having RB/G subpixels in a “rainbow” pattern). As a test, I used these settings with in-game SS at 2x and the aliasing wasn’t particularly improved. ED really seems to need SS at 4x or higher to fix the aliasing.
My System specs and ED settings are posted here: Updated 8K review, with an emphasis on Elite Dangerous